Publications

Network pharmacology and bioinformatics based investigation of Phyllanthus fraternus: herb-drug interaction study

D Joyeeta, S Ravi Adinarayan, C Nikita, R Partha Pratim, I Rakibul, Dhaked D, Satheesh Kumar Nanjappan

Journal of Biomolecular Structure and Dynamics

2024

An outlook into liposomal drug delivery of chemotherapeutic agents to combat colorectal cancer

D Paul, S Nanjappan, BG Prajapati, K Kunnambath

Colorectal Cancer, 475-487

2024

Mesua assamica (King&Prain) kosterm. Bark ethanolic extract attenuates chronic restraint stress aggravated DSS-induced ulcerative colitis in mice via inhibition of NF-κB/STAT3 …

ER Puppala, SS Yalamarthi, SL Aochenlar, N Prasad, NP Syamprasad, ...

Journal of Ethnopharmacology 301, 115765

72023

Stealth Liposomal Chemotherapeutic Agent for Triple Negative Breast Cancer with Improved Pharmacokinetics

N Kommineni, D Paul, R Saka, W Khan, S Nanjappan

Nanotheranostics 6 (4), 424-435

62022

Investigation of the effect of Acai berry on the pharmacokinetics of Atorvastatin, Alogliptin and Empagliflozin: a herb–drug interaction study

SK Nanjappan, RA Somabattini, V Ravichandiran

Journal of Pharmacy and Pharmacology 74, 1125–1132

12022

Profiling of Trace Elements and Regulatory Landscape of Dietary Herbal Supplements

SK Nanjappan, D Paul, R Ramani, S Arumugam, DK Chellappan

Environmental Challenges and Medicinal Plants: Sustainable Production …

2022

Pharmacokinetics and pharmacodynamics of peptidomimetics

SK Nanjappan, S Surendran, D Paul

Peptide and Peptidomimetic Therapeutics, 195-211

12022

Current Evidence and Future Perspectives About Herbal Therapeutics for Cancer Therapy

D Paul, A Parag, KS Aswathi, DK Chellappan, S Arumugam, ...

Handbook of Oxidative Stress in Cancer: Therapeutic Aspects, 1-29

2021

Cytochrome P450 and P-gp Mediated Herb-Drug Interactions and Molecular Docking Studies of Garcinol.

L Bolla, P Srivastava, V Ravichandiran, SK Nanjappan

Membranes, 992

82021

Evaluation of a natural compound extracted from Dolichandrone atrovirens as a novel antioxidant agent using Caenorhabditis elegans

ML Yellurkar, V Singh, VS Prasanna, P Das, S Nanjappan, R Velayutham, ...

PLoS One 19 (9), e0257702

22021

50

Shruti Surendran, David Paul, Sunil Pokharkar, Sagar Choulwar, Abhijeet Deshpande, Sanjeev Giri, N Satheeshkumar. Novel Bruton tyrosine kinase inhibitor acalabrutinib quantification by validated LC-MS/MS method: An application to pharmacokinetic study in Sprague Dawley rats

Journal of pharmaceutical and biomedical analysis, 2019; 164: 509-513

2.83

49

Satheeshkumar Nanjappan, Lavanya Bolla, Pratima Srivastava. Interactions of herbal slimming agents with CYP Substrates: an in vitro study using human liver microsomes

Drug Metabolism and Pharmacokinetics, 2019; 34, S55

2.08

48

David Paul, Patheparapu Chandrakala, Shruti Surendran, Prasanth Bitla, Nanjappan Satheeshkumar. Pharmacokinetic interaction study of novel combination of palbociclib and sorafenib for hepatocellular carcinoma in SD rats

Journal of Chromatography B, 2019; 1108: 25-31

2.44

47

A Lingesh, David Paul, VGM Naidu, N Satheeshkumar. AMPK activating and Anti adipogenic potential of Hibiscus rosa sinensis flower in 3T3-L1 cells

Journal of Ethnopharmacology; 2019; 233: 123-130

3.11

46

Paul D, Surendran S, Chandrakala P, Satheeshkumar N. An assessment of the impact of green tea extract on palbociclib pharmacokinetics using a validated UHPLC-QTOF-MS method

Biomed Chromatogr. 2019;e4469

 

1.68

45

Shruti Surendran, David Paul, Sunil Pokharkar, Abhijeet Deshpande, Sanjeev Giri, Nanjappan SatheeshKumar. A LC-MS/MS method for simultaneous estimation of a novel anti-diabetic combination of saxagliptin and dapagliflozin using a polarity switch approach: application to in vivo rat pharmacokinetic study

Analytical Methods, 2019;11: 219-226

2.07

44

Saibaba, Vishnuvardhan, JohnsiRani, Satheeshkumar. Stability-Indicating Reversed-Phase UHPLC Method Development and Characterization of Degradation Products of Almotriptan Maleate by LC-QTOF-MS/MS

Journal of Chromatographic Science; 2018: 56; 13-24

1.15

43

Johnsirani P.,Vishnuvardhan Ch., Satheeshkumar N. Metabolite characterization of ambrisentan, in in vitro and in vivo matrices by UHPLC/QTOF/MS/MS: detection of glutathione conjugate of epoxide metabolite evidenced by in vitro GSH trapping assay

Journal of Pharmaceutical and Biomedical Analysis; 155:320-328, 2018

 

3.25

    42

David Paul, Lingesh Allakonda, Amit Sahu, Shruti Surendran, Nanjappan Satheesh kumar. Pharmacokinetics and brain uptake study of novel AMPA receptor antagonist perampanel in SD rats using a validated UHPLC-QTOF-MS method

Journal of Pharmaceutical and Biomedical Analysis

149, 2018, 234-241

3.25

41

David Paul, Lingesh A, Satheeshkumar N. A validated UHPLC-QTOF-MS method for quantification of metformin and teneligliptin in rat plasma: Application to pharmacokinetic interaction study.

Journal of Pharmaceutical and Biomedical Analysis, 143, 2017, 1–8.

3.25

40

Shruti Surendran, David Paul, Ratna Sushmita, Lavanya Krishna, Nirbhay Kumar Tiwari, Sanjeev Giri, Nanjappan Satheeshkumar,; A validated LC–MS/MS method for the estimation of glimepiride and pitavastatin in rat plasma: Application to drug interaction studies. 

Journal of Chromatography B, 1046, 2017, 218–225

2.60

39

Johnsirani P.,Vishnuvardhan Ch., Lingesh A, Naidu V.G.M., Naveen Ch., Satheeshkumar N. Isolation, characterization using LC-ESI-QTOF, NMR and in vitro cytotoxicity assay of Niclosamide forced degradation products.

Journal of Pharmaceutical and Biomedical Analysis 136 (2017) 148–155

3.25

38

Vishnuvardhan C, Saibaba B, Allakonda L, Swain D, Gananadhamu S, Srinivas R, Satheeshkumar N. LC-ESI-MS/MS evaluation of forced degradation behaviour of silodosin: In vitro anti cancer activity evaluation of silodosin and major degradation products.

J Pharm Biomed Anal. 2017; 134:1-10.

3.25

37

Dhanabal Kumarasamy, Biswajit Gopal Roy, Joana Rocha-Pereira, Johan Neyts, Satheeshkumar Nanjappan, Subhasis Maity, Musfiqua Mookerjee, Lieve Naesens. Synthesis and in vitro antiviral evaluation of 4-substituted 3,4-dihydropyrimidinones.

Bioorganic & Medicinal Chemistry Letters 27 (2017) 139–142.

2.45

36

Chiguru Vishnuvardhan, Saibaba Baikadi, Roshan M Borkar, R. Srinivas, N. Satheeshkumar. In vivo metabolic investigation of silodosin using UHPLC–QTOF–MS/MS and in silico toxicological screening of its metabolites.

Journal of Mass Spectrometry, 2016; 51 (10): 677-692.

2.42

35

Vishnuvardhan Ch, Allakonda L, Srinivas R, Satheeshkumar N, Forced degradation study of racecadotril: Effect of co-solvent, characterization of degradation products by UHPLC-Q-TOF-MS/MS, NMR and cytotoxicity assay.

Journal of Pharmaceutical and Biomedical Analysis 128 (2016) 9–17

3.25

34

Chiguru Vishnuvardhan, Debasish Swain, Roshan Borkar, S. Gananadhamu , R. Srinivas , N. Satheeshkumar. Study of forced degradation behaviour of brinzolamide using LC-ESI- Q-TOF and in silico toxicity prediction.

Chromatographia 2016, 79: 1293.

1.40

33

S. Shantikumar, N. Satheeshkumar, R. Srinivas. Pharmacokinetic and protein binding profile of peptidomimetic DPP-4 inhibitor – Teneligliptin in rats using liquid chromatography–tandem mass spectrometry.

Journal of Chromatography B, 1002 (2015) 194–200.

2.60

32

Shanti Kumar S, Satheeshkumar N, Prasanth B, Lingesh A, Paul D, Srinivas R.  A sensitive and selective liquid chromatography mass spectrometry method for simultaneous estimation of anti-diabetic drugs inhibiting DPP-4 enzyme in human plasma. Overcoming challenges associated with low recovery and sensitivity.

Anal. Methods, 2015,7, 6198-6206.

1.90

31

N. Satheeshkumar, S. Shantikumar, David Paul. An Insight into Chemometrics Concepts in Pharmaceutical Analysis.

J. Pharm. Inn. Res., 2015, 2 (2), 24 – 33.

 

30

Satheeshkumar N, L. Allakonda, V. Chiguru, S. Saladi, P. Jhansi Rani. Whole Brain Cholinesterase Inhibition - Invitro and Exvivo Estimation Using Desmodium Gangeticum and its Constituents. 12th International Conference on Alzheimer's and Parkinson's Diseases and related neurological   disorders (AD/PDTM 2015),  Nice, France, March 18- 22, 2015.

Neurodegener Dis 2015;15:(suppl 1):1-1969 (DOI:10.1159/000381736).

2.84

29

Satheeshkumar, N;  Kumaraswamy R., Shantikumar S., Paul D. QBD Based Rp-HPLC Method For Screening And Analysis Of Telapravir And 7 Other Antiretroviral Agents.

Indian Drugs, 2015, 52(02), 20-33.

 

28

Satheeshkumar, N.; Nisha, N., Phytomedicines as Potential Inhibitors of β Amyloid Aggregation: Significance to Alzheimer's Disease.

Chin. J. Nat. Med, 2014, 12(11): 836-853.

 

27

Satheeshkumar, N, Shantikumar S, Komali M. Identification and quantification of aldose reductase inhibitory flavonoids in herbal formulation and extract of Gymnema sylvestre using HPLC-PDA and LC-MS/MS.

Chromatography Research International, 2014, (2014), 1- 8.

 

26

Vishnuvardhan Chiguru, Srinivas Ragampeta and N SatheeshKumar. Development and validation of a UPLC method for screening potentially counterfeit anti-hypertensive drugs using design of experiment.

Analytical Methods, 2014, 6, 4610-4616.

1.90

25

Satheeshkumar, N.; Shantikumar, S.; Srinivas, R. Pioglitazone: A Review of Analytical Methods.

Journal of Pharmaceutical Analysis, 2014;  4 (5), 295–302

 

24

Satheeshkumar, N.; Spandana, V.; Shantikumar, S.; Srinivas, R. Experimental design approach to optimize stability indicating LC method for the determination of Naftopidil in its bulk and tablet dosage form.

Journal of Young Pharmacist, 2014; 6(1):1-7

 

23

Shanti Kumar Saladi,   Sreekanth Gutala,   Krishnaveni Yadiki,   M.V.NarendraKumar and    N SatheeshKumar. Design and study of a HPLC method for the simultaneous estimation of two anti-diabetic drugs using statistical approach.

 

Analytical Methods, 2014, 6, 3291-3299.

1.90

22

Vishnuvardhan, C.; Radhakrishnanand, P.; Navalgund, S.G.; Satheeshkumar, N., Liquid chromatography/ electrospray ionisation tandem mass spectrometric study of Sitagliptin and its stressed degradation products.

Drug Res (Stuttg), 2014, 64, 668-674.

0.5

21

Vishnuvardhan, C.; Radhakrishnanand, P.; Navalgund, S.G.; Atcha, K.R.; Satheeshkumar, N., RP-HPLC Method for the Simultaneous Estimation of Eight Cardiovascular Drugs.

Chromatographia, 2014, 77(3-4), 265-275.

1.40

20

Satheeshkumar, N.; Pradeepkumar, M.; Shanthikumar, S.; Rao, V. J., Development of Validated Stability Indicating Assay Method for Simultaneous Estimation of Metformin Hydrochloride and Vildagliptin by RP-HPLC.

Drug Res (Stuttg), 2014, 64(3), 124-129.

0.5

19

Nimbarte, V. D.; Murtuza, H.; Phaniraj, S.; Shrivastava, S.; Naidu, V. G. M.; Satheeshkumar, N.; Atcha, K.R., Design, synthesis and biological evaluation of 4-(1-(4(sulphanilamide)phenyl)-3-(methyl)-1H-pyrazol-5-yl)dine urea and N-acyl derivatives as a soluble epoxide hydrolase inhibitors.

Med Chem Res, 2014, 23(5), 2178-2197.

1.61

18

Satheeshkumar, N.; Naveen, G., A Stability Indicating RP-HPLC Method For Ambrisentan-An Endothelin Receptor Antagonist.

J Chrom Sci, 2014; 52(8):894-8. (IF: 1.026

0.98

17

Shantikumar,S.; Sreekanth, G.; SurendraNath, KV.; JaferValli, S.; Satheeshkumar, N., Compatibility study between Sitagliptin and pharmaceutical excipients used in solid dosage forms.

Journal of Thermal Analysis and Calorimetry, 2014, 115(3), 2423-2428. IF: 2.20

1.95

16

Satheeshkumar, N.; Nisha, N.; Sonali, N.; Nirmal, J.; Jain, G.K.; Spandana, V., Analytical Profiling of Bioactive Constituents from Herbal Products, using Metabolomics - A Review

Nat Prod Commun, 2012, 7(8), 1111-1115.

1.24

15

P K Mukherjee, N Satheeshkumar, P Venkatesh, M Venkatesh. Lead Finding for Acetyl Cholinesterase Inhibitors from Natural Origin: Structure Activity Relationship and Scope.

Mini Reviews in Medicinal Chemistry, 11 (3), 247-262

2.66

14

Kumar NS, Nisha N, Nirmal J, Sonali N, Bagyalakshmi J (2011) HPLC Determination of Pitavastatin Calcium in Pharmaceutical Dosage Forms.

Pharm Anal Acta, 2011, 2:119.

 

13

Bhadra S, Mukherjee PK, Kumar NS, Bandyopadhyay A. Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits.

Fitoterapia. 2011;82(3):342-6

2.69

12

Satheeshkumar, N.; Mukherjee, P.K.; Bhadra, S.; Saha, B.P., Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituents.

 

Phytomedicine, 2010, 17 (3-4), 292-295. IF: 3.26

3.52

11

Kumar, N.S.; Mukherjee, P.K.; Bhadra, S.; Saha, B.P.; Pal, B.C., Acetylcholinesterase inhibitory potential of a carbazole alkaloid, mahanimbine, from Murraya koenigii.

Phytotherapy Research, 2010, 24(4), 629-631. IF: 2.36

3.09

10

Venkatesh, P.; Mukherjee, P.K.; Kumar, N.S.; Bandyopadhyay, A.; Fukui, H.; Mizuguchi, H.; Islam, N,. Anti-allergic activity of standardized extract of Albizia lebbeck with reference to catechin as a phytomarker.

Immunopharmacol Immunotoxicol, 2010; 32(2): 272–276. 

1.47

9

Mukherjee, D.; Kumar, N.S.; Khatua, T.; Mukherjee, P.K., Rapid Validated HPTLC Method for Estimation of Betulinic acid in Nelumbo nucifera (Nymphaeaceae) rhizome extract.

Phytochem Anal 2010, 21(6):556-60. IF: 2.63

3.09

8

Mukherjee, P.K.; Sahoo, A.K.; Narayanan, N.; Kumar, N.S.; Ponnusankar, S., Lead finding from Medicinal plants with hepatoprotective potentials.

 

Expert Opin Drug Discov, 2009, 4, 545-576. IF: 3.46

3.87

7

Sahoo, A.K.; Narayanan, N.; Kumar, N.S.; Rajan, S.; Mukherjee, P. K., Phytochemical and therapeutic potentials of Morinda tinctoria Roxb. (Indian mulberry).

Oriental Pharmacy and Experimental Medicine 2009 9(2), 101-105.

 

6

Venkatesh, P.; Mukherjee, P.K.; Kumar, S.N.; Nema, N.K.; Bandyopadhyay, A.; Fukui, H.; Mizuguchi, H., Mast cell stabilization and antihistaminic potentials of Curculigo orchioides rhizomes.

J Ethnopharmacol, 2009, 126, 3, 434—436. IF: 3.0

2.98

5

Mukherjee, P.K.; Kumar, V.; Kumar, N.S.; Heinrich, M., The Ayurvedic medicine Clitoria ternatea--from traditional use to scientific assessment.

 

J Ethnopharmacol, 2008,120(3) , 291-301. IF: 3.0

2.98

4

Kumar, V.; Mukherjee, K.; Kumar, S.; Mal, M.; Mukherjee, P.K., Validation of HPTLC method for the analysis of taraxerol in Clitoria ternatea.

Phytochem Anal, 2008, 19, 244-250. IF: 2.63

3.09

3

Mukherjee,P.K.; Satheeshkumar N.; Heinrich, M., Plant Made Pharmaceuticals (PMPs) - Development of Natural Health Products from Bio-Diversity.

IJPER, Vol. 42(2), 2008, 113-121.

 

2

Mukherjee, P.K.; Kumar, N.S.; Kumar, V., Exploring phytomedicines from biological diversity.

Pharmbit, 2007, 1-23.

 

1

Kumar, N.S.; Baghyalakshmi, J., Determination and Quantification of Pitavastatin Calcium in Tablet Dosage Formulation by HPTLC Method.

 

Analytical Letters, 40: 2625–2632, 2007.

1.15

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Book chapters: 05                                                                      

1. N. Satheeshkumar, David Paul, Lavanya B. Assessing Herb Drug Interactions of Herbal Products with Therapeutic Agents for Metabolic Diseases:  Analytical and Regulatory Perspectives. Studies in Natural Products Chemistry, 59, 2018, Pages 283-322

2. N. Satheeshkumar, David Paul, A. Lingesh. Liquid Chromatography-Mass Spectrometry (LC-MS) - Approaches to Adulterant Detection in Herbal Products. Tsay, H.-S., Shyur, L.-F., Agrawal, D.C., Wu, Y.-C., Wang, S.-Y. (Eds.) Medicinal Plants - Recent Advances in Research and Development, Springer International Publishing, Switzerland 2016, pp 73-95, ISBN 978-981-10-1085-9

3. N. Satheeshkumar, R.S. K Vijayan, A. Lingesh, S. Santhikumar and Ch. Vishnuvardhan. Spices: Potential Therapeutics for Alzheimer’s Disease. M.M. Essa et al. (eds.), The Benefits of Natural Products for Neurodegenerative Diseases, Advances in Neurobiology, Springer International Publishing Switzerland 2016, 12, pp 57-78. DOI 10.1007/978-3-319-28383-8_4

4. K. Mukherjee, N. Satheesh Kumar, S. Rai. Tests for antioxidant activity and their relevance to herbal medicinal products. In: Evaluation of Herbal Medicinal Products. Pharmaceutical Press, Royal Pharmaceutical Society Publishers, London, 2009, p261- 281, ISBN 978 0 85369 751 0.

5. P. K Mukherjee, KFH Nazeer Ahmed, N. Satheesh Kumar, V Kumar, P.J Houghton. Herbal medicinal products affecting memory and cognitive disorders, In: Evaluation of Herbal Medicinal Products. Pharmaceutical Press, Royal Pharmaceutical Society Publishers, London, 2009, p282-294, ISBN 978 0 85369 751 0.